Urolithin A is a metabolite compound resulting from the transformation of ellagitannins by the gut bacteria.It belongs to the class of organic compounds known as benzo-coumarins or dibenzo-α-pyrones. Its precursors – ellagic acids and ellagitannins – are ubiquitous in nature, including edible plants, such as pomegranates, strawberries, raspberries, and walnuts.

Ellagitannins are hydrolyzed from the intestine into release Ellagic acid, and this is processed from the gut microflora to urolithins through the increasing loss in 1 of its two lactones successive removal of hydroxyl groups. Once It’s consumed in the intestines, then Urolithin A powder enters the flow System of this intestine.

Mitophagy is the selective degradation of your mitochondria by autophagy. It often occurs to defective mitochondria following damage or stress. However, as we age, Mitophagy function becomes less efficient. Luckily, Urolithin A is approved to stimulate mitophagy in a conserved manner across different species.