What are the effects of coagulants and water-soluble silicides on vacuum blood collection detection Coagulation is the coagulation caused by the addition of external substances to the blood. External pathways activate clots and form them through biochemical processes. Plastic tubes require the use of spray coated blood coagulants to ensure rapid and dense clot formation. The higher density of blood coagulation promoting surface sites accelerates coagulation time. Siliceous substances (such as glass and diatomaceous earth) accelerate the formation of clots through contact with blood, and complete coagulation is formed within about 30 minutes. The amount of blood coagulant varies with the manufacturer. Procoagulants are also beneficial for separating potential fibrin formation in serum. Beneficial for the expression of prothrombin. Although these clot activators can quickly coagulate for 10 to 20 minutes, the clots are not easily separated from the serum. Blood coagulants can be added to the tube by forming small beads, which can act with the carrier on the surface of the inner tube. Quickly suspend the clot activator in the blood, and at the beginning of the clot, the carrier can dissolve both in the serum and clot. Recently, Desheng Biochemical participated in a project to assist clients in releasing a rapid serum test tube containing thrombin; The orange stopper quickly activates the blood clot within 5 minutes. It can ensure that the rapid serum test tube has the same clinical results as other commercially available serum test tubes. Desheng Biochemistry found in its research that the problem with some blood coagulants is that they must be thoroughly mixed to completely precipitate the clot. If soluble fibrin clots form, they can interfere with the accuracy of the pipetting device or solid-phase binding in immunoassays. Plasma gas can be used to introduce heteroatoms (non carbon atoms and hydrogen atoms in the molecular structure main chain) into the surface of the tube wall to accelerate coagulation, without contaminating serum or clots with adhesives or blood coagulants. The proteomic analysis of blood coagulants can also be altered by clot activators. When silica and silicate blood coagulants are sprayed onto plastic tubes, active metalloproteinases are released and the matrix is compounded. Desheng Biochemical, as a research and production manufacturer of coagulants, hereby reminds us that in order to achieve good coagulation effects, the optimal composition of coagulants and water-soluble silicides should be determined, and they should always be added to different types and sizes of blood collection vessels to enable these substances to function normally without adversely affecting the quality results of blood samples and tests.