Acetyl CoA synthase (ACS) Cat # Abt-P-1014 Acetyl CoA synthase (ACS, EC 6.2.1.3) catalyzes the reaction of free fatty acids and CoA to produce acetyl CoA. Our company's ACS is a genetic recombination product, free from animal derived viruses, with high purity and good activity. Biochemical research: The content of free fatty acids (NEFA) in serum is very low, and most of them bind to albumin. NEFA is directly related to oxidative stress, which can lead to the occurrence of diabetes by damaging islet cells and reducing the sensitivity of peripheral tissue to . The concentration of free fatty acids will increase due to diseases such as diabetes, severe liver disorder, hyperthyroidism, such as resistance/type 2 diabetes, obesity, and metabolic syndrome, and will lead to cardiovascular diseases. Enzymatic detection of free fatty acids has the advantages of speed, simplicity, high sensitivity, ease of automation, and large-scale detection. ACS is the first enzyme to initiate the free fatty acid enzymatic detection kit, so it has a very important role and significance.